Founder and Director of the Southall Black Sisters. SBS is, a multi-award-winning women’s organisation founded in 1979 to address the needs of black and minority women experiencing gender violence. It successfully campaigned for the release of Kiranjit Ahluwalia, a landmark case in which an Asian woman was convicted of the murder of her violent husband. The case reformed homicide law, creating greater awareness within and outside minority communities. Pragna is also a co-founder of Women Against Fundamentalism. She has also written extensively on race, gender and religion, including "Citizenship: Whose Rights?", "Faith in the State? Asian Women’s Struggles for Human Rights in the UK", and "Shrinking Secular Spaces: Asian Women at the Intersect of Race, Religion and Gender". She was listed in The Guardian’s Top 100 women: activists and campaigners.
In July 2019, Pragna received an honorary doctorate from Keel University in recognition of her “outstanding contribution to women’s rights, justice and secularism.”